Q: What can we do for depression? A: A lot is happening in the research and study of depression.  By looking at imaging of the brain, we can see that depression involves neurotransmitters of Seratonin, Dopamine and Norepinephrine.  The is medication that helps to adjust these chemical processes.  While medication can be helpful, there are a lot of concerns about side effects.  We know that "interpersonal counseling" and "cognitive behavioral therapy" is just as effective, if not more effective than antidepressants.  Some of the latest thinking is that treatment for depression involves growing brain cells.  This would explain why antidepressants take about 5 weeks to work, because that is how long it takes for a new brain cell to grow.  It also explains why "going to Hawaii,"  "learning a new skill," and "changing how one believes" makes us feel better.  It appears the more we use our brains, they better off we are.  People often complain when suffering from depression that they can't stop thinking negative thoughts--a one track mind.  Studies have shown that there are certain exercises and workbooks that help people rearrange their thinking, that in turn give them freedom from depression.  The results of the methods have shown positive lasting benefits as long as 2 years.